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What are Peptides?

There is a lot of buzz around peptides in the fitness world. Various peptides are recommended for burning fat, building muscle, and improving athletic performance. But what are peptides exactly?

Peptides are defined as a compound of two or more amino acids in which a carboxyl group of one is united with an amino group of another. With the elimination of a water molecule, a peptide bond is formed. To put it more simply, peptides are just small proteins. When the number of amino acids are less than 50, these are peptides. When higher than 50, these are proteins. The peptides are therefore small chains of amino acid which are present in all cells of the body. There are several kinds of peptides: oligopeptides, polymers, proteins, neuropeptides and peptide hormones. These are synthesized naturally by the body. Peptides will therefore be used primarily to make a more abundant amount of hormones in the body. The latter will then produce new hormones such as Testosterone or corticosteroids. It is these two hormones that are considered anabolic or indirect anti-inflammatory.

The positive effects of peptides

Peptides are thus one of the new generation of stimulants. They were primarily created to treat Growth Hormone (GH) deficiency. They will increase the production of Testosterone. They also improve your strength and accelerate muscle growth. Another effect is increasing your muscle tissue, as well as having a positive effect on bones and organs.

The second effect of peptides is their anti-inflammatory side. This positive effect will allow a better recovery. It also relieves pain and allows you to recover more easily from injuries (e.g. lacerations).

Peptides also provide better oxygenation of the muscles. They are also often used in endurance sports such as swimming, running, and cycling. In terms of weight, they allow the muscles to support long-term gains.

How to use peptides?

Peptides are administered, for the most part, by subcutaneous injection. So be careful not to make an Intramuscular injection. As with all injections, it is obvious that it is necessary to take precautions, especially regarding hygiene. However the process is relatively simple.

First, when buying them, peptides are stored in the refrigerator. It is necessary to wash your hands before administering every preparation. Peptides are mixed with sterilized water. After taking 2 to 1ml sterilized water with a syringe, you should let it run down the wall of the peptide vial. Let it rest for ten minutes then mix gently. It is important not to stir the solution.

To inject (so subcutaneous usage) you will need to pinch the skin before pushing the needle into the skin. Preferably choose the area under the abdomen. It should not be too near the navel. It is possible that after injecting, a bump may appear. This is quite normal and should disappear gradually as the injected liquid is absorbed.

Just check that when you insert the needle, you do not hit a key blood vessel. For that, just do a slight puncture with the needle. If you see a little blood in the syringe it means that a vessel was hit. Simply change the location of the syringe and start over.

If you need to make several injections, remember to regularly change the injection site. You can do this by injection once on the right side of the abdomen and then the next time on the left side.

Finally, it is preferable to do the injections in the evening before bedtime.

TOP 10 Peptides

1. GHRP-6
   

Causing one to be " hungry as a wolf " and having a strong gastric motility, this 1^er injectable peptide is interesting for fitness practitioners who may require support to finish their carefully prepared meals. This sudden increase in appetite that occurs around 20 minutes after the injection is related to the fact that GHRP-6 stimulates the release of a digestive hormone, Ghrelin, which is designed to cause hunger pangs. This makes it a valuable ally in weight gain treatments , which is important.

Its objective is muscle gain while helping with burning fat. It is not unusual for it to be used with steroids to amplify the effects.

This peptide is also valuable for its effectiveness in reducing inflammation and increasing wound healing, such as with tendonitis.

Note, however, that GHRP-6 should be administered before a meal or 2h after eating on an empty stomach, while the blood sugar level is low for best results.

The injections are given at a frequency of 2 per day; one before breakfast and the second before bed at night.

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2. GHRP-2

Now Unlike GHRP-6, GHRP-2 does not particularly stimulate the appetite. This is very interesting for athletes who are performing a cycle with the goal of lean mass gain.

Like GHRP-6 it shares very similar effects. This peptide offers assistance with construction of de muscle gain and for burning fat. Even more significant, it is a little more potent at stimulating secretion of growth hormone, GH.

However, the user may experience, more than GHRP-6, a modest increase of cortisol (stress hormone), prolactin (a hormone decreasing sexual desire) and aldosterone (hormone that promotes water retention).

The frequency of use is 2 injections per day; one before breakfast and the second before bed at night.

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3. MOD-GRF (1-29)

Sometimes called CJC-1295 without DAC, MOD-GRF is a peptide analog of growth hormone releasing hormone (GHRH).

Thus, this peptide is often used in combination with a peptide of category GHRP such as GHRP-2, GHRP-6, or Ipamorelin. While GHRP will stimulate the release of GHMOD-GRF will amplify this, forming a good synergistic duo.

With 100 mcg GHRP combined with 100 mcg MOD-GRF, a greater GH release will occur than with 300 mcg GHRP taken alone.

Its half-life time is about 30 minutes. It is at this point that 50% of the product has already been "consumed". This gives a relatively short duration of action which allows intermittent dosing and coordinated with GHRP for example.

MOD-GRF 1-29 is particularly effective at burning fat while accelerating muscle gain, an anti-aging effect and even promotes improved sleep, when the most important muscle growth occurs.

It may be practical to administer both simultaneously in the same syringe to limit the number of injections.

It is recommended to administer 2 injections per day; one before breakfast and the second before bed at night.

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4. Ipamorelin

Ipamorelin is one of the peptides which offers many advantages without any possible side effects. Belonging to the category of GHRP, it may optionally be combined with GRF-MOD-1 29, and is very similar to GHRP-2 and GHRP-6.

It causes considerable secretion of growth hormone by the pituitary gland and in addition has the dual effect of reducing somatostatin, a peptide hormone that inhibits the release of HGH.

Also, Ipamorelin does not stimulate the release of hormones such as cortisol and there is no significant stimulation of appetite.

A peptide of choice, therefore, especially since it is well known for its anti-aging effect.

The injections are given at a frequency of 2 per day; one before breakfast and the second before bed at night.

Anti-aging: ■ ■ ■ ■ □

HGH secretion: ■ ■ ■ ■ ■

Improved sleep: ■ ■ ■ ■ ■

Improved Cholesterol: ■ ■ ■ ■ ■

Recovery: ■ ■ □ □ □

Muscle Gain: ■ ■ ■ ■ □

Fat burning: ■ ■ ■ ■ □

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Conservation of gains: ■ ■ ■ ■ □

5. HGH fragment 176-191

HGH Fragment 176-191 is a polypeptide fragment of growth hormone, more precisely the part of the amino acids 176 to 191. This is also the part of HGH which is responsible for fat burning. It is one of the most potent peptides in regards weight loss.

It is ideal for controlling body fat and reducing abdominal fat while helping to develop muscle gain.

One can combine this peptide with GHRP-2, 6 or GHRP-PEG-MGF for dry weight gain. Similarly, for lean mass gain and a reduction in fat, it can be combined with HGH fragment MOD GRF-1-29.

Like previous peptides 2 injections per day, morning and evening.

Anti-Aging: ■ ■ ■ ■ ■

HGH secretion: ■ ■ ■ ■ ■

Improved sleep: ■ ■ ■ ■ □

Improved Cholesterol: ■ ■ ■ ■ □

Recovery: ■ ■ ■ ■ □

Muscle Gain: ■ ■ ■ □ □

Fat burning: ■ ■ ■ □ □

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Conservation of gains: ■ ■ ■ ■ □

6. Sermorelin

Sermorelin is a analog peptide of GHRH releasing hormone growth hormone. It consists of a peptide sequence of 29 amino acids. More specifically, this sequence is the 1-29 part from the 44 amino acid chain of GHRH and thus it is considered as the shortest of synthetic peptides which include all the functional parts of GHRH.

Sermorelin, which shares a similar structure to CJC-1295, is an extremely effective hormone to increase the amount of HGH.

In the 80 years, scientists have searched different peptides and more particularly GHRH to discern what part was necessary to stimulate the pituitary response. Then in testing Sermorelin as a tool for the process of anti-agingthey found that it was the famous 1-29 chain that was responsible for stimulating the endocrine gland in question. Similarly, many studies have shown that this peptide was similar to GHRH and very well tolerated by the body.

This peptide is interesting and often used in the context of anti-aging therapy but also in bodybuilding.

It is used in 2 injections a day, before breakfast and before bed.

Anti-Aging: ■ ■ ■ ■ □

HGH secretion: ■ ■ ■ ■ ■

Improved sleep: ■ ■ ■ ■ □

Improved Cholesterol: ■ ■ ■ ■ ■

Recovery: ■ ■ ■ ■ □

Muscle Gain: ■ ■ ■ □ □

Fat burning: ■ ■ ■ □ □

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Conservation of gains: ■ ■ ■ ■ □

7. CJC 1295-DAC

CJC-1295 DAC, analog GHRH(the hormone release of growth hormone), opposes MOD-GRF 1-29 by the duration of its action. This is the main difference between the two peptides.

CJC-1295 DAC has an extended duration of action, a half-life of approximately 8 days inducing a single injection per week, before breakfast. It could be called simply CJC-1295 since, without (DAC Drug Affinity Complex), MOD-GRF 1-29 is not CJC-1295 in the strict sense, but they are usually sold as distinguishing with or without CAD.

Without side effects with an appropriate assay, this peptide contributes to fat loss and muscle gain. CJC-1295 DAC could interest those wishing to rarely perform injections due to a stable rate over time rather than intermittent dosages, that provides the maximum necessary for optimal effect. Its use combined with a GHRP is interesting but not as much as with MOD-GRF whose peaks of free GHRH peptides would be coordinated with the GHRP associated.

Muscle gains: ■ ■ ■ ■ ■

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Fat burning: ■ ■ □ □ □

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8. TB500

The peptide TB-500 , also known as Thymosin Beta 4 , is made up of 43 amino acids .

TB-500 therefore is a short peptide segment, a fragment of TB-4, a naturally occurring hormone whose name it bears although it is not identical. However, the peptide sequence of TB-500 sold in the market is the same active area of ​​TB-4.

It can be recommended in the case of acute injuries as recovery may be slow, and in the case of chronic injuries. TB-500 is particularly useful on wounds such as tendinitis, muscle strains or tears, facilitating muscle recovery through action on angiogenesis, that is to say the creation of new blood vessels (vascularization).

Similarly, faced with muscle injuries resulting in loss of flexibility, TB-500 aids recovery too. It is also known for its anabolic properties with an increase of endurance and strength.

This peptide has been talked a lot in the last few years due to its appearance in several high-profile doping scandals. Indeed, this peptide is part of the category of doping S2. (Peptide hormones, growth factors and related substances).

One utilizes one injection a week with this peptide, after training or before bedtime.

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9. Melanotan II

This is a quite special peptide because it is a synthetic product specific for tanning and increasing libido. This peptide hormone that occurs naturally in the body stimulates Melanogenesis. Moreover, it also has some influence on lipid metabolism, appetite and increasing libido.

According to the proper dosage, Melatonan 2 stimulates the natural tanning mechanism to give a tan without exposure to harmful UV rays for skin, thus reducing the possible risks of damage and skin cancer. However, be careful not to abuse Melatonan II, the "Barbie Drug" as it is called, or you may not recognize yourself in the mirror.

The injection is once or twice daily before breakfast and before bed, the dose injected can be split and divided in the case of a trial.

A positive point is that the effect of Melatonan 2 remains over the long term. The effects of a cycle can last for a year or more.

Please be aware that if you are using this peptide to to increase libido stably over the entire duration of the shot, the hormone may cause spontaneous erections.

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10. PEG-MGF

PEG-MGF is a form of IGF-1, a peptide hormone which leads to the creation of new muscle cells and stimulates muscle growth. By linking to polyethylene glycol (PEG), the "pegylation will allow for increased half-life of active presence of MGF of 30 minutes for several days.

MGF is Mechano-sensitive, responsive to a mechanical stimulus, that is to say, it is a growth factor and repair process that is expressed after training or muscle damage, in the form of "urges".

Because of its long duration of action, a single injection is needed a day, after exercise or before bedtime.

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Strength gain: ■ ■ ■ □ □

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Fat burning: ■ ■ □ □ □

Conservation of gains: ■ ■ ■ ■ □

Conclusion

For people looking to boost their own production of GH ( Growth Hormone (GH) deficiency), rather than to inject it, peptides are an interesting and especially favorable solution in terms of cost.

Using these kind of peptides increases the volume of the hormone secreted by the pituitary gland, which is then converted by the liver into IGF-1. This increased amount of IGF-1 in the blood leads to many advantages in increasing the metabolism and growth of new cells.

Also, we could see that there could be synergy between peptides category GHRP and of GHRH other. The GHRP stimulates GH pulse while GHRH amplifies this momentum.

There are lots of different peptides that are useful in some cases where others would be less advantageous. We particularly think of GHRP-6 and strong appetite stimulation. But, there is something for every objective. Speaking of which, these are tools that are effective in the long term and should always be taken with due care and consideration.