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Understanding Esters and Their Differences

Trenbolone Acetate, Trenbolone Enanthate, Testosterone Cypionate, Testosterone Propionate ...

What do all these names mean? Does this have an influence on determining what products to use?

YES: the name of the ester is very important for devising your treatment.

One of the most misunderstood topics in the steroid world is the ester : that is, the mechanism by which steroids such as testosterone cypionate and Testosterone enanthate, esterified injectables such as Sustanon or Trenbolone enanthate, or acetates work in your body.

If you take a look at the internet, you will undoubtedly find countless articles that consider a form of a steroid much more effective than another.

Fitness model

The arguments about the superiority of cypionate compared to enanthate or of Sustanon compared to all other testosterones are, of course, but very common misconceptions.

Indeed, each ester has its particular benefits and when intelligently used in your treatment, it will be your perfect ally to get the results you desire.

What is an Ester?

Take the example of testosterone, which comes in different esters: cypionate, enanthate, propionate, heptylate, caproate, phenylpropionate, isocaproate, decanoate, acetate ... the list goes on and on.

In all these examples the "mother" hormone is testosterone, which has been modified by the addition of an ester in its structure.

The following question arises: What is the difference between "esterified" versions of testosterone in their use?

It is simply a matter of speed of assimilation of the molecule in the body.

Steroid ChemistryIn chemistry, the function ester denotes a characteristic group formed of an atom simultaneously bonded to an oxygen atom by a double bond.

This carbon chain is usually attached to the steroid hormone in a position referred to as beta orientation.

The esterification of a Anabolic Steroids Androgen / injectable essentially accomplishes one thing, it slows the release of the active substance from the molecule from the injection site.

This happens because the ester will have notably lowered the solubility in the water or the oil containing the steroid.

This will form a deposit in the muscle tissue, from which the flow will slow and the steroid will be absorbed in small quantities by the blood.

Generally, the more soluble the chain of the ester is, the quicker the hormone is released.

Slowing the release of the hormone is a great benefit in a cure. Indeed, without added ester, free testosterone (or other steroid hormones) would remain active in the body only for a very short period of time (usually a few hours). This would therefore require a heavy and unpleasant daily injection schedule if one wanted to maintain a high and stable level of testosterone in the body.

With the addition of an ester, the athlete can therefore reduce the frequency of injections.

The addition of an ester finally provides ease of use for users, making the therapy much less constraining.

Is any one ester stronger than another?

We must get a bit technical now.

We have thus seen that the esterification temporarily deactivates the steroid molecule and thus allows an assimilation by the organism better distributed over time.

With a blocking chain in the 17 beta position, binding to the androgen receptor is not possible, so it can not carry out any activity in the body.

Syringe FillingIn order for the compound to become active, ester must first be removed (its solubility explained in the previous chapter). This happens automatically once the compound has filtered into the bloodstream.

This will restore the hydroxyl group (OH) at position 17 beta, resulting in the attachment of the appropriate steroid receptor.

It is therefore after the disappearance of the ester that the steroid is able to have an effect on skeletal muscle tissue.

You are already beginning to understand why to consider that the Cypionate is stronger than enanthate is nonsense. Indeed, your muscles only distinguish free testosterone, regardless of which ester was used for the administration of the molecule.

There are many different esters that are used with anabolic steroids but again, they all do the same thing: reduce solubility.

Un ester such as Propionate for example, will slow down the release of a steroid for a few days, whereas the slowing down will be several weeks with an ester decanoate.

Esters therefore have no effect on the trend of aromatization to estrogen or DHT (dihydrotestosterone) of a steroid nor on the overall strength of the compound.

The differences in the results and side effects that can be noted by bodybuilders who have used different versions of the same esterified steroid are only timing issues.

For example, Enanthate will cause estrogen-related problems more easily than Sustanon simply because enanthate testosterone levels will have their peak and troughs much earlier (in 1 to 2 weeks for enanthate as opposed to 3 to 4 weeks for Sustanon).

SyringeSimilarly for testosterone suspension which is probably the most conducive to rapidly develop side effects. Simply because levels of hormones in the blood have their peaks very quickly with this steroid. Instead of waiting for weeks to see testosterone levels rise to their highest point, we are here, for the slowest, at 2 days.

Given an equal blood testosterone level, there would be no difference in the rate of conversion of aromatization or DHT between different esters. It's just the speed of the mechanism that differs.

The different esters in detail.

Now that we know what an ester is and how it works, we will examine the best known esters in alphabetical order. This will help you better control and optimize your treatment and thus achieve better results.


Chemical structure C2H4O2.

There is also talk of acetic acid. Acetate Ester delays the release of a steroid for only a few days. Contrary to what you have read, acetate esters do not increase the tendency for fat removal. Again, there is no known mechanism that would allow acetate to burn fat.

This ester is used in the oral tablets Primobolan (metenolone acetate) or Finaplix (trenbolone acetate - "Tren A") and occasionally for testosterone.


Chemical structure C8H14O2.

Cypionate is a very popular ester in the United States. Its release time is almost identical to the enanthate (10-14 days). In the US, athletes generally believe that cypionate is more potent than inhaler. Yet there is very little difference between the two. The Enanthate ester is actually slightly smaller than cypionate, and thus releases a tiny (perhaps a few milligrams) more steroids in addition when compared.


Chemical structure C10H20O2.

We also talk about decanoic acid. The decanoate ester is most often used with nandrolone (as in Deca-Durabolin). It is present in virtually every corner of the world. Testosterone Decanoate is also the longest active constituent acting in Sustanon, greatly extending its release duration. The release time with decanoate compounds is barely less than one month. However, it has recently been found that levels appear to drop significantly after two weeks. To keep blood levels more consistent, athletes will follow a weekly injection schedule.


Chemical structure C7H14O2.
It is one of the most important esters used in the manufacture of steroids, most commonly seen with testosterone. It is also used in other compounds such as Primobolan Depot.
Enanthate will allow to have a balanced level of the hormone during about 10 to 14 days.
Although in the context of medicine, enanthate compounds are often injected on a biweekly or monthly basis, athletes, meanwhile, prefer 1 or 2 injections per week to help maintain a consistent level of testosterone.


Chemical structure C6H12O2.

This ester has a somewhat shorter life than enanthate and is only used with testosterone in a "blend" as Sustanon or Omnadren.

Testosterone molecule


Chemical structure C9H10O2.

The phenylpropionate ester will extend release of the active steroid for a few days longer than the propionate ester.

To maintain blood levels similar to propionate, the injections are made at least two times per week. Deca-Durabolin is the product most commonly observed with a phenylpropionate ester (nandrolone phenylpropionate - "NPP") but it is also used with testosterone in Sustanon and Omnadren.


Chemical structure C3H6O2.

Also known as Carboxyethane or Propionic Acid. The propionate ester will slow down the release of a steroid for several days.

To allow blood levels to increase fast, the propionate compounds are usually injected two to three times per week. Testosterone propionate is one of the most well-known steroids.


Chemical structure C11H22O2.

Undecanoate is not a very common ester. It appears to be used only in the preparation of nandrolone (Dynabolan) and oral testosterone undecanoate (Andriol). Since this ester is chemically very similar to undecylenate (there are only two more hydrogen atoms), it has a similar release time (about 2-3 weeks).

There is no reason to believe that it has unique properties compared to other esters because it is used in oral preparation Andriol.

Andriol actually works very badly to provide testosterone, reinforcing the idea that oral administration really is not the ideal use of esterified testosterone.


Chemical structure C11H20O2.

This ester is very similar to decanoate, containing one carbon atom more. its release time is also very similar (about 2-3 weeks), which extends perhaps 1 or 2 days more than decanoate.

The Undecylenate seems to be reserved exclusively for veterinary preparation Equipoise (boldenone Undecylenate), the Equipoise works great for athletes.

Again, weekly injections are most common.


Muscular torso

Each ester thus has its particularity concerning the release of the hormone in the body. But the release time is also dependent on another factor, a technical factor: the weight of the ester.

The longer the ester will be long plus this one will be heavy. In the case of testosterone enanthate for example, 250 mg of esterified steroid (Testosterone enanthate) is equal to only 180 free testosterone mg for 70mg of enanthate.

You understand now, because the propionate ester is shorter, it is the ester which is the lightest.

So although the advent of esters is a valuable advance in steroids, they do not change the anabolic steroid strength.

Testosterone remains testosterone, trenbolone rest of the trenbolone, etc ... Some will argue that a form of ester of a particular hormone is much better than another: it is a view totally unfounded and erroneous.

You now have all the cards in hand to best design your treatments, and if any doubts still exist, do not hesitate to contact one of our consultant who will be happy to help you.

Have a nice cycle.

The team of Top Steroids Online.

Comments (6)

  1. Marciotr February 15 2018 at 2: 58

    Testosterone undecanoate is a hormonal relaxant of NEBIDO. Gostaria of saber se o decanoato de testosterona teria o mesmo efeito?

    1. Benjamin
      Benjamin March 15 2018 at 6: 00

      Good morning,

      Tendrá los mismos efectos

  2. Alisson February 25 2017 at 11: 23

    ácido acético não é ester, e ácido carboxílico

  3. Dyno 22 2016 August at 1: 34

    Thank you for this in-depth explanation of the esters that will lie less stupid !!!!

  4. Oscar January 27 2016 at 8: 21

    Salve, volevo chiedere is a programming avete da seguire riguardante e prodotti di modalità Assunzione dei prodotti che Dovrei acquistare da Voi.
    Thank you

  5. Darkside March 16 2015 at 3: 46

    Excellent article on esters.

Leave a comment

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